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Date: 29-12-2021
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Cytidine Triphosphate Synthesis
Cytidine triphosphate (CTP) is produced by amination of UTP by CTP synthetase (Fig. 1), with glutamine providing the nitrogen. Some of this CTP is dephosphorylated to CDP, which is a substrate for ribonucleotide reductase. The dCDP product can be phosphorylated to dCTP for DNA synthesis or dephosphorylated to dCMP that is deaminated to dUMP.
Figure 1: Synthesis of CTP from UTP. [Note: CTP, required for RNA synthesis, is converted to dCTP for DNA synthesis.] ADP = adenosine diphosphate; Pi = inorganic phosphate.
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"عادة ليلية" قد تكون المفتاح للوقاية من الخرف
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ممتص الصدمات: طريقة عمله وأهميته وأبرز علامات تلفه
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المجمع العلمي للقرآن الكريم يقيم جلسة حوارية لطلبة جامعة الكوفة
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