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Date: 9-9-2020
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Claisen Condensation
Because esters can contain α hydrogens they can undergo a condensation reaction similar to the aldol reaction called a Claisen Condensation. In a fashion similar to the aldol, one ester acts as a nucleophile while a second ester acts as the electrophile. During the reaction a new carbon-carbon bond is formed. The product is a β-keto ester. A major difference with the aldol reaction is the fact that hydroxide cannot be used as a base because it could possibly react with the ester. Instead, an alkoxide version of the alcohol used to synthesize the ester is used to prevent transesterification side products.
Example 23.7.1: Claisen Condensation
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الصحة العالمية: شركات التبغ تستهدف جيلا جديدا بهذه الحيل
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بكل عزيمة ونشاط.. كيف يمكن للطلبة مواجهة الامتحانات؟
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المجمع العلمي يُصدِر الكتاب الخامس من سلسلة (علماؤنا السابقون)
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